Michael S. Blouin
Professor
E-Mail:mailto:blouinm@science.oregonstate.edu
, Office Phone: 541-737-2362, Lab Phone: 737-4360 FAX: 541-737-0501,
Address: Department of Zoology,
I have diverse interests in basic and applied evolutionary genetics. I teach General Genetics (Bi311), Population Genetics (Gen 430/530) and Evolution (Bi445/545). My past research focused on phenotypic evolution and landscape genetics in amphibians. The current research foci in my lab are:
(1) Evolutionary genetics of parasites, and host-parasite evolution (see example publications below). Past and recent work focused on what controls effective size, gene flow and genetic structure in helminth parasites (nematodes and trematodes). Our most recent work focuses on the molecular evolution of disease resistance loci. We are currently collaborating on an NIH-funded study of loci in snails (Biomphalaria glabrata) that confer resistance to trematodes (Schistosoma mansoni – a serious pathogen of humans).
(2) We are using microsatellite loci to reconstruct the pedigree of an entire population of steelhead trout, Onchorynchus mykiss (photo) for purposes of comparing the relative reproductive success of hatchery and wild fish, and for studying what controls the effective sizes of these populations. See recent media coverage of this work (2007 Associated Press, Reuters; 2009; Science News, NPR). This research is an offshoot of my interests in molecular methods for pedigree reconstruction in natural populations. See example publications below.
Current members of
the lab
Ivan Phillipsen. (philliiv@science.oregonstate.edu) 541-737-4360. PhD student. Amphibian landscape genetics.
Kaitlin Bonner (bonnerk@science.oregonstate.edu) 541-737-4360. PhD student. Resistance genes in Biomphalaria-Schistosoma system
Melanie Marine (marinem@science.oregonstate.edu) Lab manager. 541-737-4360
Eli – lab mascot; photo ca. 1998.
Former students
Kirsten
Monsen – Assistant Professor at
Eric
Hoffman Assistant Professor at
Charles Criscione Assistant Professor, Biology, Texas A&M. 979-845-0917 (ccriscione@mail.bio.tamu.edu) PhD Spring 2005. Molecular ecology of trematodes.
Jacob Tennessen (:tennessj@science.oregonstate.edu). Post-doc with J. Akey,
Other alumni
Román Vilas Peteiro; Post Doc
2003-2005; parasite population genetics; Now with Dept. Genética, Facultad de Veterinaria, Campus de Lugo,
27002, Lugo, Spain. vilasr@usc.es
Bill Ardren; Post Doc 2001-2002; steelhead pedigree project. Now with USFWS william_ardren@fws.gov
Hitoshi Araki (hitoshi.araki@eawag.ch)
Post-doc 2003-2007; Steelhead project.
Now with Eawag, Swiss Federal Institute of
Aquatic Science and Technology
Deb Finn. Post-doc 2006-2007; Aquatic insect landscape genetics; with Dave Lytle. Now at Eawag, Swiss Federal Institute of Aquatic Science and Technology Debra.Finn@eawag.ch
Becky Cooper. Lab manager 2003-2007. bkymonster@gmail.com
Vindhya Amarasinghe. Lab Manager 2008-2009
Selected Publications: See also COMPLETE LIST OF REFERENCES)
Evolutionary genetics
of parasites, host-parasite interactions
Theron, A., C. Coustau, A. Rognon, S. Gourbičre, and M.S. Blouin. 2008 Effects of laboratory culture on compatibility between snails and schistosomes. Parasitology, 135:1179-1188. PDF
Bender, R.C. C.P. Goodall, M.S. Blouin and
C.J. Bayne. 2007. A regulatory variant of Biomphalaria glabrata SOD1 and its role in susceptibility/resistance to Schistosoma mansoni, Developmental and Comparative
Immunology, 9: 874-878.
PDF
Tennessen, J.A. and M.S. Blouin. 2008. Balancing selection at a frog antimicrobial peptide locus: fluctuating immune effector molecules? Molecular Biology and Evolution 25:2669–2680. PDF
Tennessen J.A. and M.S. Blouin. 2007. Selection for antimicrobial peptide diversity in frogs leads to gene duplication and low allelic variation. Journal of Molecular Evolution 65:605-615 PDF
Criscione, C.D., B. Cooper and M.S. Blouin. 2006. Parasite genotypes identify source populations of migratory fish more accurately than fish genotypes. Ecology 87:823-828. PDF
Criscione, C.D. and M.S. Blouin. 2006. Minimal selfing, few clones, and no among-host genetic structure in a hermaphroditic parasite with asexual larval propagation. Evolution, 60:553-562. PDF
Criscione, C.D., R. Poulin and M.S. Blouin. 2005. Molecular ecology of parasites: elucidating ecological and microevolutionary processes. Molecular Ecology 14:2247-2257. PDF
Criscione, C.D. and M.S. Blouin. 2005. Effective sizes of macroparasite populations: a conceptual model. Trends in Parasitology 21: 212-217. PDF
Criscione, C.D. and M.S. Blouin. 2004. Life cycles shape parasite evolution: comparative population genetics of salmon trematodes. Evolution 58:198-202. PDF
Blouin,
Blouin, M.S., C.A. Yowell, C.H. Courtney and J.B. Dame (1995) Host movement and the genetic structure of populations of parasitic nematodes. Genetics 141: 1007-1014. PDF
Pedigree
reconstruction methods, applications to steelhead trout
Araki, H., B. Cooper and M.S. Blouin. 2009. Carry-over effect of captive breeding reduces reproductive fitness of wild-born descendents n the wild. Biology Letters doi: 10.1098/rsbl.2009.0315 PDF
Araki, H., B. Cooper and M.S. Blouin. 2007. Genetic effects of captive breeding cause a rapid, cumulative fitness decline in the wild. Science, 318: 100-103. PDF
Araki, H., W.R. Ardren, E. Olsen, B.
Cooper and M.S. Blouin. 2007. Reproductive success of captive-bred
steelhead trout in the wild: evaluation of three hatchery programs in the
Araki, H., R.S. Waples, W.R. Ardren, B. Cooper and M.S. Blouin. 2007. Effective population size of steelhead trout: influence of variance in reproductive success, hatchery programs, and genetic compensation between life-history forms. Molecular Ecology 16:953-966 PDF
Araki, H. and M.S. Blouin. 2005. Unbiased estimation of relative reproductive success of different groups: evaluation and correction of bias caused by parentage assignment errors. Molecular Ecology, 13:4097-4109 PDF
Blouin, M.S. 2003. DNA-based methods for pedigree reconstruction and kinship analysis in natural populations. Trends in Ecology and Evolution 18: 503-511. PDF
Blouin, M.S., M. Parsons, V. Lacaille,
and
Amphibian
evolutionary and landscape genetics
Phillipsen,
Hoffman, E.A., Schueler, F.W., A.G. Jones and M.S. Blouin. 2006. An analysis of selection on a color polymorphism in the northern leopard frog. Molecular Ecology, 15:2627-2641. PDF
Hoffman, E.A., F.W. Schueler and M. S. Blouin. 2004. Effective population sizes and temporal stability of genetic structure in Rana pipiens, the Northern leopard frog. Evolution 58:2536-2545. PDF
Monsen, K.J. and M.S. Blouin. 2004. Extreme isolation by distance in the Cascades frog, Rana cascadae. Conservation Genetics 5:827-835. PDF.
Blouin, M.S. (1992) Genetic correlations among morphometric traits and rates of growth and differentiation in the green tree frog, Hyla cinerea. Evolution 46: 735-744. PDF
Blouin, M.S., and M.L.G. Loeb (1991) Effects of environmentally-induced development rate variation on head and limb morphology in the green tree frog, Hyla cinerea. American Naturalist 138: 717-728. PDF
|
Return to: |
||